FODZYME®
FODZYME®
Tasteless enzyme powder formulated to break down the FODMAPs fructan, GOS, and lactose in your meal so you can enjoy it.
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FODZYME®
"It took a few but Fodzyme was able to restore my gut’s balance so that I don’t need Miralax to have regularity."
How It Works
Feel The Difference With Your First Meal
Mix directly or apply evenly on meals.
Double dosage when feasting. Chew well. Enjoy.
Unlock New Foods
Our current formula effectively breaks down the FODMAPs fructan (e.g., garlic, onion, wheat, ...), GOS (e.g., legumes, nuts), and lactose (e.g., dairy products). We are actively developing a solution for polyols (e.g., apple, avocado, mushrooms) such as sorbitol and mannitol.
** FODZYME® significantly reduces fructan (a FODMAP) in wheat, barley and rye products, not gluten. Fructan is often the real trigger in individuals with non-celiac gluten sensitivity.
FODZYME® can help unlock a long list of healthy, nutritious and delicious foods like,
And many more delicious and nutritious foods
Tasteless Formulation
FODZYME® is formulated as a tasteless powder to ensure maximum contact between its digestive enzymes and FODMAP-containing foods, allowing for more effective breakdown of FODMAPs during digestion. Unlike capsules, the powder mixes directly with food, optimizing enzyme performance and supporting better digestive relief.
Our formulation consists of clinically and scientifically studied microbial enzymes characterized at both academic institutions, and research partners.
ACTIVE INGREDIENTS:
ENZYME BLEND (32MG PER G)
Our fructan hydrolase is the first ever enzyme to target fructans like inulin, fructo-oligosaccharides (FOS), and levan.
Our alpha-galactosidase enzyme can effectively break down the galacto-oligosaccharides (GOS) or galactans (“O” in FODMAPs).
Our lactase enzyme (also called β-D-galactosidase) can break down lactose (the “D” in FODMAPs).
Other ingredients: dextrin (from non-GMO corn)
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
Science-Backed difference
Of the fructan mass broke down within 30 minutes in simulated gastric conditions.1*
Of members reported an improvement in bloating after using FODZYME® for 4 weeks.2*
Of members said they would be disappointed if FODZYME® ceased to exist.3*
Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)
FODZYME® was tested in SHIME®, a scientifically validated model of human digestion, to measure its efficacy. Unlike a low FODMAP diet that depletes beneficial short-chain fatty acids (SCFAs), FODZYME® limited but did not eliminate SCFA production, supporting colonic health while easing symptoms 1.
- Kenny Castro Ochoa, Samant S, Liu A, et al. In Vitro Efficacy of Targeted Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Enzymatic Digestion in a High-Fidelity Simulated Gastrointestinal Environment. Gastro Hep Advances. 2022;2(3):283-290. doi:https://doi.org/10.1016/j.gastha.2022.10.011
- Based on a survey including n=174 FODZYME® customers evaluating self-perceived efficacy.
- Based on a survey including n=220 FODZYME® customers evaluating self-perceived efficacy.
Not a Probiotic. Not a Pill.
Engineered specifically to break down FODMAPs
Patent-pending formula with first-ever fructan-targeting enzyme.
Powder form for superior efficacy
Powder format allows the enzymes to mix directly with food.
Scientifically validated
Backed by peer-reviewed scientific publications, demonstrating its effectiveness.
Rigorously tested
Third-party tested for enzyme activity, allergens, and contaminants.
Certified low-FODMAP
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In Control, Wherever You Are.
FODZYME®
Home Kit
Sustainable jar. Ideal for home-cooked meals.
FODZYME®
Home Kit
Sustainable jar. Ideal for home-cooked meals.
Why Members Love FODZYME®
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Brooke H.
"FODZYME makes my life more normal again. I don’t avoid and/or dread eating out anymore. I can travel with less stress."
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Denise H.
"It has changed my life! I can eat foods I have eaten in years! It really works!"
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Madeline H.
"So helpful to take the stress out. Now I don't bloat and I don't have discomfort after eating. And meals are blissfully not stressful!"
Hi 👋, We’reCo-FoundersAnjie and David!
Anjie Liu
Anjie created FODZYME® after battling IBS and the limitations of a low-FODMAP diet. A Harvard-trained physicist and Forbes 30 Under 30 honoree, she leads with a personal mission: to help people enjoy food without fear.
David Hachuel, MPH
David brings deep experience in gut health technology, including founding auggi.ai (acquired by Seed Health). With degrees from Harvard, NYU, and Cornell, he drives FODZYME®’s science, product, and growth to make digestive freedom a reality.
Our Scientific Advisory Board Includes Experts In Gastroenterology, Biotechnology, Computational Biology, And Nutrition, Representing World-Class Institutions.
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William D. Chey, MD
Advisor, Professor of Gastroenterology at the University of Michigan and Board member at the American College of Gastroenterology (ACG) and Rome Foundation
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Shalaka Samant, PhD
Founding Scientist at Kiwi Biosciences, former postdoctoral researcher at the Yale University School of Medicine
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Thomas Wallach, MD
Advisor, Assistant Professor at SUNY Downstate Medical Center, Pediatric Gastroenterology
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Jocelyn Wells, MS, RDN
A dietitian with a Master's in Clinical Nutrition, Jocelyn leads FODZYME®'s healthcare partnerships. She bridges the latest research in digestive health and nutrition guidelines to help clinicians bring digestive relief to patients navigating IBS and FODMAPs.
Frequently Asked Questions
What exactly is FODZYME®?
What exactly is FODZYME®?
FODZYME®is a tasteless enzyme powder designed to break down FODMAPs (fructan, GOS, and lactose) in food to make meals more digestible. It's formulated specifically for people with FODMAP sensitivities.
What ingredients does FODZYME® contain?
What ingredients does FODZYME® contain?
- Fructan Hydrolase:One of FODZYME’s core innovations, this enzyme helps break down fructans and inulin found in foods like garlic, onions, and wheat.
- Alpha-galactosidase:Targets GOS (galacto-oligosaccharides) present in beans and legumes, aiding digestion.
- Lactase:Simplifies the digestion of lactose, commonly found in dairy products.
- Dextrin:Sourced from non-GMO maize/corn, used to stabilize the enzymes, ensuring they remain effective throughout digestion.
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
Is FODZYME® allergen-friendly?
Is FODZYME® allergen-friendly?
Yes, FODZYME® is:
- Certified low FODMAP by Monash University and FODMAP Friendly
- Vegan-friendly
- Non-GMO
- Gluten-free
- Dairy-free
- Soy-free
- Egg-free
- Casein-free
- Free from artificial colors and flavors
- Manufactured in the USA with global ingredients
What foods does FODZYME® help digest?
What foods does FODZYME® help digest?
FODZYME® targets three primary FODMAP groups—fructans, galacto-oligosaccharides (GOS), and lactose—which are common triggers for digestive discomfort. Its enzyme blend works on foods like garlic, onions, wheat, beans, lentils, dairy products, and certain vegetables, breaking these FODMAPs into easily digestible sugars.
Key Food Groups Supported and Example Foods:
- Fructans:Garlic, onions, leeks, wheat, barley, asparagus, artichokes, Brussels sprouts, and cashews.
- GOS:Chickpeas, lentils, black beans, red kidney beans, soy milk (whole bean), pistachios, and oats.
- Lactose:Milk, yogurt, ice cream, soft cheeses (ricotta, cottage cheese), and cream.
How do I take FODZYME®?
How do I take FODZYME®?
- Mix Directly:Mix FODZYME® directly or apply evenly on meals. It’s tasteless.
- Alternate Method:If you can’t mix, sprinkle FODZYME® and chew with the first bite.
- Adjust Dosage:Dosage is personal—double the dose if extra sensitive or for large meals.
- Temperature Note:Allow hot foods to cool slightly before applying (below 140 °F / 60 °C). As a rule of thumb, adding FODZYME® is okay if the meal is cool enough that it won’t burn.
- Enjoy:Chew well and enjoy your meal!
How is FODZYME® different from other digestive enzymes?
How is FODZYME® different from other digestive enzymes?
FODZYME® is the first enzyme blend custom-made to tackle FODMAPs—the fermentable carbs that wreak havoc on sensitive tummies. Its secret sauce is fructan hydrolase, a unique enzyme that breaks down problematic fructans in garlic, onions, and wheat, while lactase and alpha-galactosidase cover a broad range of FODMAP offenders.
Offered in a powdered form for immediate action, FODZYME® mixes instantly with your food—cutting down FODMAP content by up to 90% and easing symptoms like bloating and gas. It’s Monash University-certified and backed by clinical trials, making it a science-driven solution for those seeking real dietary freedom.
How quickly does FODZYME® work? When will I feel something?
How quickly does FODZYME® work? When will I feel something?
FODZYME® begins breaking down FODMAPs immediately upon contact with food. In simulated gastric conditions, it degraded up to 90% of FODMAPs like fructans within 30 minutes. This rapid action prevents undigested FODMAPs from reaching the colon, where they typically ferment and cause symptoms such as bloating and gas.
Most users report symptom relief 4–8 hours after consuming a FODMAP-rich meal—aligned with the time it takes for digested food to reach the colon.
Can I use FODZYME® every day?
Can I use FODZYME® every day?
Yes, FODZYME®is designed for safe daily use. Its enzymes are naturally occurring and work specifically on FODMAPs without interfering with normal digestion or nutrient absorption. Regular use can help manage symptoms and expand dietary choices for those following a low FODMAP diet.